67,095 research outputs found

    Are Galaxies Optically Thin to Their Own Lyman Continuum Radiation? II. NGC 6822

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    Halpha and UBV photometry of NGC 6822 are used to study the distribution of OB stars and HII regions in the galaxy and to determine whether individual regions of the galaxy are in a state of ionization balance. Four distinct components of the Halpha emission (bright, halo, diffuse and field) differentiated by their surface brightnesses are identified. We find that approximately 1/2 of all OB stars in NGC 6822 are located in the field while only 1/4 are found in the combined bright and halo regions, suggesting that OB stars spend roughly 3/4 of their lifetimes outside ``classical'' H II regions. Comparing the observed Halpha emission with that predicted from stellar ionizing flux models, we find that although the bright, halo and diffuse regions are probably in ionization balance, the field region is producing at least 6 times as much ionizing flux as is observed. The ionization balance results in NGC 6822 suggest that star formation rates obtained from Halpha luminosities must underestimate the true star formation rate in this galaxy by about 50%. Comparing our results for NGC 6822 with previous results for the spiral galaxy M33, we find that the inner kiloparsec of M33 is in a more serious state of ionization imbalance, perhaps due to its higher surface density of blue stars.Comment: Replaced version should now compile with standard aastex style files. 28 pages, aastex preprint format. Accepted in ApJ. Hardcopies of figures available on request to [email protected]

    Investigating microstructural variation in the human hippocampus using non-negative matrix factorization

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    In this work we use non-negative matrix factorization to identify patterns of microstructural variance in the human hippocampus. We utilize high-resolution structural and diffusion magnetic resonance imaging data from the Human Connectome Project to query hippocampus microstructure on a multivariate, voxelwise basis. Application of non-negative matrix factorization identifies spatial components (clusters of voxels sharing similar covariance patterns), as well as subject weightings (individual variance across hippocampus microstructure). By assessing the stability of spatial components as well as the accuracy of factorization, we identified 4 distinct microstructural components. Furthermore, we quantified the benefit of using multiple microstructural metrics by demonstrating that using three microstructural metrics (T1-weighted/T2-weighted signal, mean diffusivity and fractional anisotropy) produced more stable spatial components than when assessing metrics individually. Finally, we related individual subject weightings to demographic and behavioural measures using a partial least squares analysis. Through this approach we identified interpretable relationships between hippocampus microstructure and demographic and behavioural measures. Taken together, our work suggests non-negative matrix factorization as a spatially specific analytical approach for neuroimaging studies and advocates for the use of multiple metrics for data-driven component analyses

    Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care

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    Author can archive publisher's pdf. Free via Creative Commons: CC-BENCHTOBEDSIDE-2.0. © 2012 BioMed Central Ltd

    A case study of MMO2's Madic: A framework for creating mobile internet systems

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    Mobile Internet applications on ubiquitous mobile networks allows real-time, anywhere, anytime connectivity to services. Due to its scalability and potential cost savings, mobile communication is being increasingly applied in the business and consumer communities to create innovative data and voice application, which run over the Internet infrastructure. This paper reports on a case study at an organisation that created an innovative approach to developing mobile applications developed by third party independent developers. A conceptual wireless reference model is presented that was used to define the various system components required to create effective mobile applications

    Myasthenia gravis as a 'stroke mimic'

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